Neofloxacin–S 10%


Neofloxacin–S 10% 

Composition: 1 ml solution for injection contains:

Enrofloxacin 100 mg

Indications: Treatment of various primary and secondary bacterial infections of the

respiratory, and gastrointestinall tract, in cattle and pigs.

Cattle: coli-septicemia, coli-diarrhea, pasteurellosis, salmonellosis, staphylococcosis,

mycoplasmosis, secondary infections in viral diseases, mastitis and others.

Pigs: coli-diarrhea, coli-septicemia, salmonellosis, pasteurellosis, enzootic and bacterial

bronchopneumonia, MMA syndrome and atrophic rhinitis.

Contraindications: The drug is not given very young animals, or animals hypersensitive

to enrofloxacin. The drug is not given to pregnant sows.Preparation should not be used

in prophylaxis.

Side effects: After drug administration may be associated with gastrointestinal disorders

(vomiting and diarrhea), skin rash and hyper-arousal CNS. Also, it is possible

photosensitization if treated animals exhibited the effects of sunlight. At the site of

administration may be a transient local tissue reaction (swelling, pain, redness).

Fluorinated quinolones may cause arthropathy and possibly lameness in young animals,

which occurs due to damage to the articular cartilages. Are also possible allergic


Target species: Cattle, calves and pigs.

Dosage and method of administration: The medicine is given subcutaneously (s.c.) in

the usual places or intramuscular (i.m.), (in the middle of the neck muscles) in cattle, and

pigs ear. Cattle and pigs therapeutic dose ranges from 2.5 to 5 mg enrofloxacin per 1 kg

of body weight, or 1-2 mL injection solution per 40 kg of body weight, depending on the

severity of the infection.The drug is given at 24-hour intervals over 3-5 days. It is

necessary to determine more precisely animal weight to avoid sub-dosing.

Instructions for proper use of drugs:

Do not give medicine to animals that do not belong to the target species.Do not give

drug intavenous.If drug dose for cattle and hogs more than 10 mL, and pigs is greater

than 5 mL, the drug should be given on several injection places.Use of this medicine

must be based on clinical findings, and if possible results of antibiogram.Use of this drug

should be limited to cases in which the cause showed resistance to other antibiotics and

the bacteriological confirmation of the diagnosis and susceptibility testing of pathogens

justify its use.

The drug must be applied in the doses and manner prescribed, or otherwise, may be the

cause of resistance to fluoroquinolones and decrease the efficiency of other quinolones

in therapy because of possible cross-resistance.

Withdrawal period: Meat of treated bovine animals is not for human consumption

during the course of therapy and 14 days after the last application of the medicine, and

the meat of pigs during the course of therapy and 13 days after the last application of the

medicine. Milk of cows is not for human consumption during treatment and 7 days after

last administration of the drug.

Special considerations:

Pregnancy and lactation: The drug is not used in pregnant animals.

Special considerations for persons administering the veterinary medicinal product

to animals:

In applying the drug should avoid direct contact with skin and mucous membranes, or

eyes. Hands after each application should be washed and medicine kept out of the reach

of children.

Interactions: The product should not be administered concurrently with tetracycline,

macrolide antibiotics, tiamphenicol and fluorphenicol, because they all reduce or

completely antagonize the effect of enrofloxacin, while simultaneously with

sulphonamides and trimetoprimom, increasing its toxicity.

Do not use simultaneously with theophylline because the elimination of theophylline may

be delayed.

Special precautions for disposal and destruction of drug

Unused drug or drug residues shall be destroyed in accordance with applicable


Special considerations for storing drugs: In the original container at temperatures up

to 25˚C. Keep out of the reach of children.

Method of issue: on prescription of veterinarian

Shelf Life: In the original package 2 years.

Shelf life after opening: 28 days

ATCvet code: QJ01MA90

Packaging: bottle of dark glass type II of 100 mL and 500 mL, closed with bromobutyl

rubber stopper and aluminum cap.

Number and date of registration:

1x 100ml 323-01-00521-14-001 date 10.06.2015.

1x 500ml 323-01-00522-14-001 date 10.06.2015.

Producer: “FM Pharm”, Subotica, 024/548-130



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