Composition: 1 ml solution for injection contains:

Dexamethasone-sodium-phosphate 2.64 mg

Indications: Treatment of diseases of the locomotor system of animals, as well as a

variety of inflammation of joints (arthritis, periarthritis, poliarthritis), inflammation of the

tendon sheath and tendon (tendinitis and tendovaginitis), inflammation (bursitis),

inflammation of muscles (myositis), nerves (neuritis), painful injuries: sprains

(dislocations), bruises (contusions), sprains (distortions), broken bones (fractures),

allergic reaction, and ketosis, puerperal paresis, skin diseases and trauma during

delivery. Dexamethasone is used as symptomatic therapy with antibiotics in the

treatment of inflammation of the udder (mastitis) and MMA syndrome of sows, as well as

in the treatment of inflammatory conditions of the respiratory system of horses, cattle,

pigs, dogs and cats.

Contraindications: application of the drug is contraindicated for animals hypersensitive

to glucocorticoids or any component of the drug, in pregnancy (except in gravidity

toxemia), recent surgical procedure (because it prevents the healing of wounds), with

wounds that do not heal, glaucoma, edema, renal and heart failure, diabetes, steroid

diabetes mellitus, hyperadenokorticism, blood dyscrasias, and ulceration of the gastric

mucosa, acute tuberculosis, deep corneal ulcers, osteoporosis and demodicosis. The

drug is not indicated for viral infections (during viremia), as well as laminitis in horses. It

is not given for bacterial infections that were not treated with bactericidal antibiotics.

Side effects: While a single dose of medication is generally well tolerated, its long-term

use can cause serious side effects. Application of high doses of glucocorticoids in the

period of a few weeks may cause suppression of the hypothalamic-pituitary-

adrenocortical shaft. System use of corticosteroid, particularly at the beginning of

therapy with this drug can cause polyuria, polidipsya and polifagya. Later there may

appear a weakness of the muscles, osteoporosis and lethargy, as well as the

appearance of hemorrhagic gastroenteritis, pancreatitis, dysfunction of liver and kidneys.

There may occur glycosuria, leukopenia, trombocitopeny.Because of

immunosuppressive effects of corticosteroids susceptibility of animals to bacterial and

viral infections is increased. At long term usage its possible retention of sodium and

water, with consequent edema. May cause anaphylactic reactions, in which case you

should immediately apply adrenalin.

Target species: horses, cattle, pigs, dogs and cats,

Dosage and method of administration:

The drug is given intramuscularly or locally in the burned tissue (intraarticular,

perarticular, intrabursal) in a daily dose of:

Horses, cattle: 2.5 mL/100kg body weight local 2-4ml

Foals, calves: 0.5 mL/10kg body weight local 1-2ml

Pigs: 0.5 mL/10kg body weight local 1-2ml

Cats & Dogs: 0.25 mL/5kg body weight local 0.25-1ml

The drug is administered once, but depending on the severity of the inflammatory

process, in large animals dose can be repeated after 1 – 2 days, pigs and dogs after 1-2

days, and in cats after 2-3 days.

Instructions for proper use of drugs: Therapy implement with the recommended

therapeutic doses, because any increase in dose causes unwanted harder effects.

Intraarticular use of this drug performed under strict aseptic conditions, and since

exclude bacterial infection, fracture or aseptic necrosis of the bone. Be careful in the

treatment of various inflammatory conditions because dexamethasone, as well as other

glucocorticosteroids, may mask the clinical picture and thus facilitate the spread of


The application of high doses of glucocorticoids in the period of a few weeks may cause

suppression of the hypothalamic-pituitary-adrenocortical axis. Because of that it is

recommended to gradually reduce the dose of glucocorticoids until the therapy ends.

Withdrawal period: Meat of treated cattle and pigs is not for human consumption during

treatment or for 21 days after the last application of medicine. Milk of cows is not for

human consumption during treatment or 84 hours after the last application of medicine.

Medicine is not given to horses whose meat is intended for human consumption.

Special warnings

For use on animals: When given to cows in lactation it reduces milk production during

3-5 days, with what animal owners must be familiar. All glucocorticoids, including

dexamethasone can cause laminitis at susceptible horses.

It is not given 24 hours before the race.

Estrogens potentiate the effect of glicocortikoids when used simultaneously. NSAIL

potentiate the side effects of glicocortikoids on digestive system. Glicocortikoids reduce

the efficiency of bacteriostatic antibiotics. Corticosteroids are not applied at the time of

vaccination and 3-4 weeks before and after vekcination, due to its immunosupressive

effects.Antihistamines and barbiturates stimulate metabolism corticosteroids by induction

of liver enzymes, and thus reduce the activity dexamethasone. On the other hand, the

use of dexamethasone reduces the time of barbiturates.

Use during pregnancy and lactation

Do not recommend the use of corticosteroids during gravidity.The drug applied in early

pregnancy can cause fetal malformations.In the last third of pregnancy can cause

premature birth, fetal death, placental retention and metritis.At lactating cows can lead to

a reduction in milk production.

Special considerations for people who give animals medicine

Avoid direct contact with the product.Wash hands after application.Do not eat or drink

while handling with product.In case of contact with eyes, they should be immediately

flushed with water.

Special precautions for disposal and destruction of drug

Unused drug or drug residues shall be destroyed in accordance with applicable


Storage: Store in original container at temperatures up to 25 °C, out of reach of children.

Shelf life: 2 years.

Shelf life after first opening: 28 days at temperatures up to 25 ˚C

Method of issuance: On prescription of veterinarian

Packaging: Glass bottle of 20 mL and 50 mL.

ATCvet code: QH02AB02

Number and date:

1x 20ml 323-01-0591-11-002 date 25.07.2012.

1x 50 mL 232-01-0592-11-002 date 25.07.2012.

Producer: “FM Pharm”, Subotica, 024/548-130



There are no reviews yet.

Be the first to review “Neomethason”