Neoceftiofur HCl 5%

Description

Neoceftiofur HCl 5%

Composition: 1 ml solution for injection contains:

Ceftiofur hydrochloride 50 mg

Indications: Treatment of infections caused by microorganisms susceptible to ceftiofur.

Cattle:

-For The treatment of respiratory tract infections caused by the Pasteurella multocida,

Mannheimia haemolytica and Haemophilus somnus.

– For the treatment of acute interdigital necrobacillosis (panaricijum, contagious bovine

lameness) caused by Fusobacterium necrophorum and Bacteroides melaninogenicus

(Porphyromonas asaccharolytica).

-For The treatment of acute puerperal metritis (within 10 days after calving) caused by:

Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum.

Pigs:

For the treatment of respiratory tract infections caused by the Pasteurella multocida,

Actinobacillus pleuropneumoniae and Streptococcus suis.

Contraindications

Do not give any medicine to animals hypersensitive to ceftiofur and other beta-lactam

antibiotics. Do not give the drug intravenously.

Side effects

In cattle there may be a reaction at the injection site in the form of swelling and

discoloration subcutis and / or fascia. This reaction usually occurs 10 days after the

injection and can last for 28 days (or longer).

In pigs there are also occurring mild local tissue reactions at the injection site, which can

persist for up to 20 days after treatment and pass spontaneously.

Possible occurrence of hypersensitivity reactions.

Target species

Cattle, swine

Dosage and method of administration:

Cattle: intramuscular and subcutaneous application

-Treatment of respiratory disease: 1 mg ceftiofur / kg bw / day (eq. 1 mL of the drug / 50

kg bw) over 3-5 days.

– Treatment of acute interdigital necrobacillosis: 1 mg ceftiofur / kg bw / day (eq. 1 mL of

the drug / 50 kg body weight) for 3 days.

– Treatment of acute puerperal metritis, within 10 days after calving: 1 mg ceftiofur / kg

bw / day (eq. 1 mL of the drug / 50 kg bw) for 5 days.

Pigs: intramuscular application

3 mg ceftiofur / kg bw / day (eq. 1 mL of the drug / 16 kg body weight) for 3 days.

Instructions for proper use of medicine:

Always, when possible, the drug should only be based on the findings of susceptibility

testing.

The drug should be used only for the treatment of diseases for which there are already

aware or are expected to respond poorly to other classes of antimicrobial drugs.

Withdrawal period: Meat of bovine animals is not for human consumption during

treatment and 8 days after the last drug administration. No restrictions for milk. Meat of

treated pigs is not for human consumption during treatment and 5 days after the last

drug administration.

Special considerations:

For administration to animals.

Because of the antagonistic activity, are not applied at the same time with other

bacteriostatic drugs, such as tetracycline, macrolide antibiotics, and sulphonamides.

In pigs should be avoided s.c. application of the drug.

In case of hypersensitivity reactions should be discontinued, if necessary, apply

adrenalin, antihistamines and corticosteroids.

Use during pregnancy and lactation

Although studies in laboratory animals suggest that ceftiofur not manifest foetotoxic,

teratogenic and reproductive toxic effects, no proper studies on the target species. When

a pregnant animal preparation used with caution.

Special warnings for persons administering veterinary medicinal product to

animals

People sensitive to penicillins and cephalosporins should avoid handling the drug.

In case of hypersensitivity reactions, such as swelling of the face, lips, eyes, or difficulty

breathing, should seek immediate medical attention.

Special precautions for disposal and destruction of drug

Unused drug or drug residues should be destroyed in accordance with applicable

regulations.

Storage: Store in original container at a temperature at 2 to 8 ˚ C.

Keep out of the reach of children.

Shelf life in original packaging: 2 years.

Shelf life after opening: 4 weeks at a temperature at 2 to 8 ˚ C.

Method of issuance: on prescription of veterinarian

Packaging: Glass vials of 20 ml, 50 ml, 100 ml and 250 ml

ATCvet code: QJ01DA90

Number and date of registration:

1x 20ml 323-01-17-09-002 from 18.09.2013.

1 x 50 mL 323-01-18-09-003 from 18.09.2013.

1 x 100ml 323-01-19-09-004 from 18.09.2013.

1 x 250ml 323-01-20-09-005 from 18.09.2013..

Producer: “FM Pharm”, Subotica, 024/548-130