Neoceftiofur HCl 5%
Composition: 1 ml solution for injection contains:
Ceftiofur hydrochloride 50 mg
Indications: Treatment of infections caused by microorganisms susceptible to ceftiofur.
-For The treatment of respiratory tract infections caused by the Pasteurella multocida,
Mannheimia haemolytica and Haemophilus somnus.
– For the treatment of acute interdigital necrobacillosis (panaricijum, contagious bovine
lameness) caused by Fusobacterium necrophorum and Bacteroides melaninogenicus
-For The treatment of acute puerperal metritis (within 10 days after calving) caused by:
Escherichia coli, Arcanobacterium pyogenes and Fusobacterium necrophorum.
For the treatment of respiratory tract infections caused by the Pasteurella multocida,
Actinobacillus pleuropneumoniae and Streptococcus suis.
Do not give any medicine to animals hypersensitive to ceftiofur and other beta-lactam
antibiotics. Do not give the drug intravenously.
In cattle there may be a reaction at the injection site in the form of swelling and
discoloration subcutis and / or fascia. This reaction usually occurs 10 days after the
injection and can last for 28 days (or longer).
In pigs there are also occurring mild local tissue reactions at the injection site, which can
persist for up to 20 days after treatment and pass spontaneously.
Possible occurrence of hypersensitivity reactions.
Dosage and method of administration:
Cattle: intramuscular and subcutaneous application
-Treatment of respiratory disease: 1 mg ceftiofur / kg bw / day (eq. 1 mL of the drug / 50
kg bw) over 3-5 days.
– Treatment of acute interdigital necrobacillosis: 1 mg ceftiofur / kg bw / day (eq. 1 mL of
the drug / 50 kg body weight) for 3 days.
– Treatment of acute puerperal metritis, within 10 days after calving: 1 mg ceftiofur / kg
bw / day (eq. 1 mL of the drug / 50 kg bw) for 5 days.
Pigs: intramuscular application
3 mg ceftiofur / kg bw / day (eq. 1 mL of the drug / 16 kg body weight) for 3 days.
Instructions for proper use of medicine:
Always, when possible, the drug should only be based on the findings of susceptibility
The drug should be used only for the treatment of diseases for which there are already
aware or are expected to respond poorly to other classes of antimicrobial drugs.
Withdrawal period: Meat of bovine animals is not for human consumption during
treatment and 8 days after the last drug administration. No restrictions for milk. Meat of
treated pigs is not for human consumption during treatment and 5 days after the last
For administration to animals.
Because of the antagonistic activity, are not applied at the same time with other
bacteriostatic drugs, such as tetracycline, macrolide antibiotics, and sulphonamides.
In pigs should be avoided s.c. application of the drug.
In case of hypersensitivity reactions should be discontinued, if necessary, apply
adrenalin, antihistamines and corticosteroids.
Use during pregnancy and lactation
Although studies in laboratory animals suggest that ceftiofur not manifest foetotoxic,
teratogenic and reproductive toxic effects, no proper studies on the target species. When
a pregnant animal preparation used with caution.
Special warnings for persons administering veterinary medicinal product to
People sensitive to penicillins and cephalosporins should avoid handling the drug.
In case of hypersensitivity reactions, such as swelling of the face, lips, eyes, or difficulty
breathing, should seek immediate medical attention.
Special precautions for disposal and destruction of drug
Unused drug or drug residues should be destroyed in accordance with applicable
Storage: Store in original container at a temperature at 2 to 8 ˚ C.
Keep out of the reach of children.
Shelf life in original packaging: 2 years.
Shelf life after opening: 4 weeks at a temperature at 2 to 8 ˚ C.
Method of issuance: on prescription of veterinarian
Packaging: Glass vials of 20 ml, 50 ml, 100 ml and 250 ml
ATCvet code: QJ01DA90
Number and date of registration:
1x 20ml 323-01-17-09-002 from 18.09.2013.
1 x 50 mL 323-01-18-09-003 from 18.09.2013.
1 x 100ml 323-01-19-09-004 from 18.09.2013.
1 x 250ml 323-01-20-09-005 from 18.09.2013..
Producer: “FM Pharm”, Subotica, 024/548-130